What do you get when you cross an Alpha-1 MZ gene carrier/hypertensive momma with a developing baby who has ZZ Alpha-1?
ANSWER: SEVERE PREECLAMPSIA
Some amazing research is going on at Yale by Dr. Irina Buhimschi. She has identified that misfolded Alpha-1 protein shows up in the urine of preeclampsia-bound expectant mothers.
I've found 2 articles so far:
Key To Pre-eclampsia May Be Found In Misfolded Proteins In Urine http://www.sciencedaily.com/releases/2009/01/090130182911.htm
Preeclampsia May Stem From Malformed Proteins
Yale researchers say discovery could lead to earlier diagnosis, treatment http://www.healthday.com/Article.asp?AID=623632
Random thoughts from a severe preeclampsia survivor and two time NICU mom who passionately believes in helping to find a cure for her daughters' genetic disorder: Alpha-1 Antitrypsin Deficiency.
Showing posts with label preeclampsia and heart disease risk. Show all posts
Showing posts with label preeclampsia and heart disease risk. Show all posts
Sunday, February 01, 2009
Wednesday, September 10, 2008
Post Traumatic Stress
I wrote an entry on the Preeclampsia Survivors blog based on an interaction I had with a coworker whose wife developed severe preeclampsia. I thought I'd cross-post it here:
http://preeclampsiasurvivors.blogspot.com/2008/09/post-traumatic-stress.html
http://preeclampsiasurvivors.blogspot.com/2008/09/post-traumatic-stress.html
Sunday, December 09, 2007
Preeclampsia and Heart Disease Risk
Frankly, this is not new information for me, but when the American Heart Association sent me an email with this newsblast inside, it was a wake up call. Preeclampsia survivors do not have good odds when it comes to risks for heart disease or stroke.
So ladies, may I issue a health challenge? How about we take the new year to create a better version of ourselves? Whether that is living a happier life to improve your mental health or making your physical health important to you, it is up to you.
Newsflash:
Women Who Experience Preeclampsia More Likely To Develop Heart Disease, Study Says
Women who experience preeclampsia -- a condition in which blood pressure increases late in pregnancy -- have a higher risk of developing high blood pressure, heart disease or stroke later in life than women who do not experience the condition, according to a study published in the Nov. 1 edition of BMJ, the Washington Post/Hartford Courant reports. For the study, British researchers analyzed data from 25 studies that involved more than 3.4 million women, 198,252 of whom had preeclampsia during pregnancy and 21,958 of whom had been diagnosed with cardiovascular disease or cancer.
Women who had preeclampsia were four times more likely than women who did not have the condition to develop high blood pressure within 14 years, the study found. The risk of having heart disease or stroke within 10 years nearly doubled for women who had preeclampsia, compared with those who did not have the condition. The study also found that a woman's risk for heart disease increased the earlier during pregnancy she developed preeclampsia. The researchers found that preeclampsia did not increase women's risk for breast cancer or other cancers. The study is available online.
I had Grace 5 1/2 years ago. I guess I only have 4 more years before heart disease or stroke may hit me. Sigh. I'd better get myself to a cardiologist for a work up and figure out how I can live a healthier lifestyle. Life isn't a guarantee, but I know that all of my preeclampsia survivor friends are some of the strongest ladies I know. We can do it ladies. We can!
With much anticipation of a healthier me and you!
Jen
So ladies, may I issue a health challenge? How about we take the new year to create a better version of ourselves? Whether that is living a happier life to improve your mental health or making your physical health important to you, it is up to you.
Newsflash:
Women Who Experience Preeclampsia More Likely To Develop Heart Disease, Study Says
Women who experience preeclampsia -- a condition in which blood pressure increases late in pregnancy -- have a higher risk of developing high blood pressure, heart disease or stroke later in life than women who do not experience the condition, according to a study published in the Nov. 1 edition of BMJ, the Washington Post/Hartford Courant reports. For the study, British researchers analyzed data from 25 studies that involved more than 3.4 million women, 198,252 of whom had preeclampsia during pregnancy and 21,958 of whom had been diagnosed with cardiovascular disease or cancer.
Women who had preeclampsia were four times more likely than women who did not have the condition to develop high blood pressure within 14 years, the study found. The risk of having heart disease or stroke within 10 years nearly doubled for women who had preeclampsia, compared with those who did not have the condition. The study also found that a woman's risk for heart disease increased the earlier during pregnancy she developed preeclampsia. The researchers found that preeclampsia did not increase women's risk for breast cancer or other cancers. The study is available online.
I had Grace 5 1/2 years ago. I guess I only have 4 more years before heart disease or stroke may hit me. Sigh. I'd better get myself to a cardiologist for a work up and figure out how I can live a healthier lifestyle. Life isn't a guarantee, but I know that all of my preeclampsia survivor friends are some of the strongest ladies I know. We can do it ladies. We can!
With much anticipation of a healthier me and you!
Jen
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